Effect
What Toxic Thicket does
Thornlash spikes inside Venom pools erupt a second time.
Toxic Thicket is a legendary chest item that raises Toxic Thicket for Thornlash only. It lasts for the rest of the run. One copy is all it needs; extra copies do nothing.
Source
How to get Toxic Thicket
Chest items drop from treasure chests out in the wilds — spend gold to open one, and each chest costs more than the last. Rarer items are rarer drops, so Luck (from Fortune or the Censer) makes a legendary pull more likely. On every floor’s plaza the Wishing Well grants the exact item you name once per floor: the surest way to complete a build around Toxic Thicket.
Skill
Toxic Thicket and Thornlash
Thornlash
A line of thorns erupts toward the thickest foes, rooting them briefly.
Without Thornlash in your build this item does nothing, so take the skill first and wish for the item once the skill is upgraded.
Builds
Builds Toxic Thicket completes
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